Gonggong Sea Snails Unveil Natural Antibiotics for Future Pharmaceuticals

A recent study has unveiled promising insights into the antimicrobial properties of Gonggong sea snails, specifically the meat extracts of Leavistrombus turturella. Conducted by Viruly Lily from the Department of Aquatic Product Technology at Raja Ali Haji Maritime University, this research sheds light on the potential of these snails as a source of natural antibiotics.

The research builds on previous findings that highlighted the ability of Gonggong sea snail meat to inhibit harmful bacteria like Escherichia coli and Staphylococcus aureus. However, the specific proteins responsible for these antimicrobial effects had remained a mystery—until now. The study focused on identifying the histone H2A protein, a type of antimicrobial peptide (AMP) commonly found in gastropods.

Using high-performance liquid chromatography (HPLC), the team analyzed the amino acid profiles of the snail extracts. They discovered that the histone H2A proteins from Gonggong sea snails showed a remarkable 80% similarity to those found in other mollusks, particularly the Fiscus gracilis. This similarity is significant, as it suggests that these snails share a common evolutionary trait that enhances their antimicrobial capabilities.

The amino acid profiles revealed a mix of cationic, anionic, and hydrophobic amino acids, which are crucial for the antimicrobial properties of these peptides. As Lily stated, “These results can be used as the first information for developing AMPs from GSS meat extract in the field of natural preservative exploration and pharmaceuticals.”

For the maritime sector, this research opens up exciting commercial opportunities. With the growing demand for natural preservatives and alternatives to synthetic antibiotics, the use of Gonggong sea snails could position themselves as a viable source for the food industry and pharmaceutical applications. Not only does this align with the trend towards sustainable and natural products, but it also highlights the potential for local fisheries to diversify their offerings and tap into new markets.

As the world increasingly leans towards natural solutions, the findings published in ‘BIO Web of Conferences’ could pave the way for innovative uses of marine resources, showcasing the untapped potential of our oceans. This study not only emphasizes the importance of marine biodiversity but also serves as a reminder of the valuable resources that lie beneath the waves, waiting to be explored.

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